Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality
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چکیده
منابع مشابه
Endotoxin-induced lethality in neonatal mice is counteracted by interleukin-10 (IL-10) and exacerbated by anti-IL-10.
The lethal effects occurring in neonatal (<24-h-old) BALB/c mice after challenge with 25 mg of lipopolysaccharide (LPS) per kg of body weight were significantly counteracted by pretreatment with recombinant interleukin-10 (rIL-10; 25 or 50 ng/mouse). Concordantly, blockage of endogenous IL-10 with the SXC1 monoclonal antibody increased LPS-induced mortality. Both IL-10 and SXC1 modulated the re...
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ژورنال
عنوان ژورنال: Frontiers in Medicine
سال: 2021
ISSN: 2296-858X
DOI: 10.3389/fmed.2021.672658